The U.S. Food and Drug Administration approved a new use for Botox Cosmetic for the temporary improvement in the appearance of moderate to severe lateral canthal lines, known as crow’s feet, in adults. Botox Cosmetic is the only FDA approved drug treatment option for lateral canthal lines. The FDA approved Botox Cosmetic in 2002 for the temporary improvement of glabellar lines, known as frown lines, in adults. OnabotulinumtoxinA is marketed as Botox and Botox Cosmetic. Botox Cosmetic is manufactured by Allergan.